Mutated EGFR-IN-1 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1421372-66-8 | Cat. No. | BCP28639 |
| Name | Mutated EGFR-IN-1 | ||
| Synonyms | AZD9291-Des acryl analogue;Osimertinib analog;AZD9291DA; | ||
| SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)CCN(C)C)OC | ||
| Chemical Name | |||
| Formula | C25H31N7O | M. Wt | 445.57 |
| Purity | 98％ | Storage | Store at 4-8°C |
| Description | Mutated EGFR-IN-1 is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. | ||
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