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CAS No. | 1914078-41-3 | Cat. No. | BCP49715 |
Name | eCF506 | ||
Synonyms | derivative 11a;NXP-900; | ||
SMILES | CC(C)(C)OC(=O)NC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)CCN4CCC(CC4)N(C)C)OC | ||
Chemical Name | |||
Formula | C26H38N8O3 | M. Wt | 510.63 |
Purity | 98% | Storage | Store at 4-8°C |
Description | eCF506 is a potent and highl selective inhibitor towards Src tyrosine kinase with a 1000-fold selectivity over ABL. eCF506 inhibits SRC at subnanomolar concentration (IC50 < 0.5 nM). It is said that eCF506 is the first drug candidate of a second generation of Src inhibitors that will not only help to understand the complexity of some cancers but also the development of safer combination therapies. |
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