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CAS No. | 2561529-96-0 | Cat. No. | BCP44575 |
Related Products | 2490716-96-4(MRTX849 analog 24) 2326521-71-3(MRTX849 ) | ||
Name | MRTX849 acid | ||
Synonyms | |||
SMILES | C=C(C(=O)N1CCN(CC1CC#N)C2=NC(=NC3=C2CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)OCC6CCCN6CCC(=O)O)F | ||
Chemical Name | |||
Formula | C34H37ClFN7O4 | M. Wt | 662.15 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2. LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50s between 0.25 and 0.76 μM). |
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