Vanzacaftor

  • Chemical Properties
CAS No. 2374124-49-7 Cat. No. BCP49728
Name Vanzacaftor
Synonyms VX-121;VX 121;VX121;
Formula C32H39N7O4S M. Wt 617.76
  • Biological Activity
Description Vanzacaftor (VX-121) is an orally active noval corrector of Cystic fibrosis transmembrane conductance regulator (CFTR). Vanzacaftor improves processing and trafficking of CFTR protein as well as increases chloride transport in triple combined with Tezacaftor and Deutivacaftor. Vanzacaftor-Tezacaftor-Deutivacaftor is safe and well tolerated, improving lung function, respiratory symptoms, and CFTR function with cystic fibrosis, which is promising for research in the field of cystic fibrosis diseases.
Pathways Ion Channel/Membrane Transporter 
Targets CFTR 

Structure

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