索喹替尼
| CAS号 | 2226636-04-8 | 货号 | BCP49733 |
| 中文名 | 索喹替尼 | ||
| 英文名 | Soquelitinib | ||
| 中文别名 | |||
| 英文别名 | CPI-818;CPI 818;CPI818; | ||
| 分子式 | C25H30N4O4S2 | 分子量 | 514.66 |
| 生物活性 | Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8+ cells that possess enhanced T effector function. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Others | ||
结构式
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