依帕斯他
CAS号 | 82159-09-9 | 货号 | BCP04572 |
中文名 | 依帕斯他 | ||
英文名 | Epalrestat | ||
中文别名 | 益帕瑞司特; 依帕司他; | ||
英文别名 | ONO-2235; ONO 2235; ONO2235; Sorbistat; | ||
分子式 | C15H13NO3S2 | 分子量 | 319.39 |
生物活性 | Epalrestat may affect or delay progression of the underlying disease process. Data from six clinical trials were evaluated, and it was determined that epalrestat 50 mg 3 times/day may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms as compared with baseline and placebo. Epalrestat may serve as a new therapeutic option to prevent or slow the progression of diabetic neuropathy. Epalrestat significantly increased the amplitude of 3 cpm waves on EGG and improved the spectral analytical parameters of heart rate variability. These findings suggest that epalrestat is useful for the treatment of diabetic gastroparesis . Epalrestat is a highly effective and safe agent for the treatment of diabetic neuropathy . | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | Aldose Reductase |
结构式

本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!