吴茱萸碱
| CAS号 | 518-17-2 | 货号 | BCP02282 |
| 中文名 | 吴茱萸碱 | ||
| 英文名 | Evodiamine | ||
| 中文别名 | |||
| 英文别名 | Isoevodiamine; | ||
| 分子式 | C19H17N3O | 分子量 | 303.36 |
| 生物活性 | Evodiamine (Isoevodiamine), an alkaloid extract from Evodiae Fructus exhibits antitumor activities against the human tumor cells. Evodiamine induces the substantial amount of apoptosis both in Bcl-2- and Akt-overexpressing U937 cells but not in human peripheral blood mononuclear cells via caspase-independent apoptotic pathways.Evodiamine Evodiamine also inhibits tumor necrosis factor (TNF)-induced NF-kappaB and Akt activation but it has no effect on JNK or p38 MAPK activation.In addition, Evodiamine is an human topoisomerase I inhibitor. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Others | ||
结构式
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