氨来呫诺
| CAS号 | 68302-57-8 | 货号 | BCP28222 |
| 中文名 | 氨来呫诺 | ||
| 英文名 | Amlexanox | ||
| 中文别名 | 氨来诺; | ||
| 英文别名 | Amoxanox; AA-673; AA673; AA 673; CHX 3673; CHX-3673; CHX3673; | ||
| 分子式 | C16H14N2O4 | 分子量 | 298.3 |
| 生物活性 | Amlexanox, also known as AA-673 and CHX 3673, is an anti-inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers. | ||
| 信号通路 | NFκB | ||
| 靶 点 | IκB/IKK | ||
结构式
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