Larotaxel New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 156294-36-9 | Cat. No. | BCP27660 |
| Name | Larotaxel | ||
| Synonyms | TAX-109;TAX 109;TAX109;XRP-9881;XRP 9881;XRP9881;RPR-109881A;PNU 100940;PNU-100940;PNU100940;192573-38-9(2H2O); | ||
| SMILES | CC1=C2C(C(=O)C34CC3CC5C(C4C(C(C2(C)C)(CC1OC(=O)C(C(C6=CC=CC=C6)NC(=O)OC(C)(C)C)O)O)OC(=O)C7=CC=CC=C7)(CO5)OC(=O)C)OC(=O)C | ||
| Chemical Name | |||
| Formula | C45H53NO14 | M. Wt | 831.91 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Larotaxel is a semi-synthetic derivative of the taxane 10-deacetylbaccatin III with potential antineoplastic activities. Larotaxel binds to tubulin, promoting microtubule assembly and stabilization and preventing microtubule depolymerization, thereby inhibiting cell proliferation. As it represents poor substrate for P-glycoprotein-related drug resistance mechanisms, this agent may be useful for treating multi-drug resistant tumors. Larotaxel penetrates the blood brain barrier. | ||
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