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Troparil Chemical Structure

Troparil

Data Sheet For research use only. Not for human use.
Cat. No. :BCP18912CAS No. :74163-84-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 74163-84-1 Cat. No. BCP18912
Name Troparil
Synonyms (–)-2β-Carbomethoxy-3β-phenyltropane; WIN 35,065-2; β-CPT;
SMILES CN1C2CCC1C(C(C2)C3=CC=CC=C3)C(=O)OC
Chemical Name
Formula C16H21NO2 M. Wt 259.34
Purity 98% Storage Store at 4-8°C
Description Troparil (also known as (–)-2β-Carbomethoxy-3β-phenyltropane, WIN 35,065-2, or β-CPT) is a stimulant drug used in scientific research. Troparil is a phenyltropane-based dopamine reuptake inhibitor (DRI) that is derived from methylecgonidine. Troparil is a few times more potent than cocaine as a dopamine reuptake inhibitor, but is less potent as a serotonin reuptake inhibitor,and has a duration spanning a few times longer, since the phenyl ring is directly connected to the tropane ring through a non-hydrolyzable carbon-carbon bond. The lack of an ester linkage removes the local anesthetic action from the drug, so troparil is a pure stimulant. This change in activity also makes troparil slightly less cardiotoxic than cocaine. The most commonly used form of troparil is the tartrate salt, but the hydrochloride and naphthalenedisulfonate salts are also available, as well as the free base.
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