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Sodium Channel

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Sodium Channel

结构式 货号 产品名称 CAS号
VX-548 结构式
 BCP49209 VX-548 2649467-58-1
Suzetrigine is a blocker of sodium channel protein type 10 subunit alpha. Suzetrigine acts as an analgesic.
SLC13A5-IN-1 结构式
 BCP48912 SLC13A5-IN-1 2227548-95-8
SLC13A5-IN-1 is a selective sodium-citrate co-transporter (SLC13A5) inhibitor.
GDC0276 结构式
 BCP25410 GDC0276 1494581-70-2
GDC0276 is a selective, reversible, orally bioavailable small-molecule sodium channel blocker that is selective for Nav1.7, which is expressed primarily on peripheral nociceptor C-fiber neurons and is required for pain sensing in humans.
RY785 结构式
 BCP45758 RY785 1393748-80-5
RY785 is a selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 µM) that does not affect Cav2 calcium channels.
EIPA 结构式
 BCP44873 EIPA 1154-25-2
EIPA is a selective blocker of Na+/H+ antiport.
CRMP2-Ubc9-NaV1.7 inhibitor 194 结构式
 BCP44631 CRMP2-Ubc9-NaV1.7 inhibitor 194 2241651-99-8
CRMP2-Ubc9-NaV1.7 inhibitor 194 is a CRMP2-Ubc9-NaV1.7 inhibitor.
NAV 26 结构式
 BCP40913 NAV 26 1198160-14-3
NAV 26 is a selective Nav1.7 channel blocker.
GX-936 结构式
 BCP39481 GX-936 1235406-09-3
GX-936, also known as PF-05196233, is a Nav1.7 inhibitor.
Dyclonine 结构式
 BCP38594 达克罗宁 586-60-7
Dyclonine is n-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. It has a role as a topical anaesthetic. It is a member of piperidines and an aromatic ketone.
Licarbazepine 结构式
 BCP35919 利卡西平 29331-92-8
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. It is an active metabolite of oxcarbazepine. In addition, an isomer of licarbazepine, eslicarbazepine ((S)-(+)-licarbazepine), is an active metabolite of eslicarbazepine acetate. Oxcarbazepine and eslicarbazepine acetate are inactive on their own, and behave instead as prodrugs to licarbazepine and eslicarbazepine, respectively, to produce their therapeutic effects.
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