Sisunatovir HCl
| CAS号 | 1903763-83-6 | 货号 | BCP40521 |
| 中文名 | Sisunatovir HCl | ||
| 英文名 | Sisunatovir HCl | ||
| 中文别名 | |||
| 英文别名 | Sisunatovir hydrochloride;RV521 Hydrochloride;RV-521 HCl; | ||
| 分子式 | C23H23ClF4N4O | 分子量 | 482.91 |
| 生物活性 | Sisunatovir, also known as RV521, is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. RV521 exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Oral bioavailability in preclinical species ranged from 42 to >100% with evidence of highly efficient penetration into lung tissue. In healthy adult human volunteers experimentally infected with RSV, a potent antiviral effect was observed with a significant reduction in viral load and symptoms compared to placebo. | ||
| 上下游产品 | 1903763-82-5（Sisunatovir） | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | RSV | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！