Sisunatovir HCl 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP40521CAS号：1903763-83-6纯度：98%

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CAS号	1903763-83-6	货号	BCP40521
关联产品	1903763-82-5（Sisunatovir）
中文名	Sisunatovir HCl
英文名	Sisunatovir HCl
中文别名
英文别名	Sisunatovir hydrochloride;RV521 Hydrochloride;RV-521 HCl;
SMILES	C1CC12C3=C(C=C(C=C3)F)N(C2=O)CC4=NC5=C(N4CCCC(F)(F)F)C=CC(=C5)CN.Cl
化学名称
分子式	C23H23ClF4N4O	分子量	482.91
纯度	98%	配送	惯例下常温包邮
产品描述	Sisunatovir, also known as RV521, is a highly potent fusion inhibitor with efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses. RV521 exhibited a mean IC50 of 1.2 nM against a panel of RSV A and B laboratory strains and clinical isolates with antiviral efficacy in the Balb/C mouse model of RSV infection. Oral bioavailability in preclinical species ranged from 42 to >100% with evidence of highly efficient penetration into lung tissue. In healthy adult human volunteers experimentally infected with RSV, a potent antiviral effect was observed with a significant reduction in viral load and symptoms compared to placebo.