雷贝拉唑
| CAS号 | 117976-89-3 | 货号 | BCP06638 |
| 中文名 | 雷贝拉唑 | ||
| 英文名 | Rabeprazole | ||
| 中文别名 | |||
| 英文别名 | Aciphex;LY 307640;LY-307640;LY307640; | ||
| 分子式 | C18H21N3O3S | 分子量 | 359.44 |
| 生物活性 | Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. | ||
| 信号通路 | Ion Channel/Membrane Transporter | ||
| 靶 点 | Proton Pump | ||
结构式
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