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CAS号 | 117976-89-3 | 货号 | BCP06638 |
中文名 | 雷贝拉唑 | ||
英文名 | Rabeprazole | ||
中文别名 | |||
英文别名 | Aciphex;LY 307640;LY-307640;LY307640; | ||
SMILES | |||
化学名称 | |||
分子式 | C18H21N3O3S | 分子量 | 359.44 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. |
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