富马酸沃诺他赞新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP05635CAS号：1260141-27-2纯度：98%

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CAS号	1260141-27-2	货号	BCP05635
关联产品	881681-00-1（沃诺拉赞） 881681-01-2（沃诺拉赞富马酸盐）
中文名	富马酸沃诺他赞
英文名	Vonoprazan fumarate
中文别名	富马酸凡诺帕胺;沃拉帕赞富马酸盐;
英文别名	TAK-438 fumarate;TAK438 fumarate;TAK 438 fumarate;
SMILES	CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O
化学名称
分子式	C17H16FN3O2S.C4H4O4	分子量	461.46
纯度	98%	配送	惯例下常温包邮
产品描述	TAK-438 is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date. TAK-438 inhibits gastric H+, K+-ATPase activity in a concentration-dependent manner. Under neutral conditions (pH 7.5), the inhibitory activity of TAK-438 is almost the same as that under weakly acidic conditions (pH 6.5). TAK-438 does not inhibit Na+, K+-ATPase activity even at concentration 500 times higher than their IC50 values against gastric H+,K+-ATPase activity. TAK-438 inhibits gastric H+, K+-ATPase in a K+-competitive manner with Ki of 3 nM.

富马酸沃诺他赞 新