雷尼司他新

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货号：BCP14386CAS号：147254-64-6纯度：98%

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CAS号	147254-64-6	货号	BCP14386
中文名	雷尼司他
英文名	Ranirestat
中文别名
英文别名	AS-3201; AS3201; AS 3201; SX-3201; SX3201; SX 3201;
SMILES
化学名称
分子式	C17H11BrFN3O4	分子量	420.19
纯度	98%	配送	惯例下常温包邮
产品描述	Ranirestat, also known as AS-3201; SX-3201, is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy by Dainippon Sumitomo Pharma and PharmaKyorin. It has been granted orphan drug status. The drug is to be used orally. Aldose reductase is an enzyme that catalyzes one of the steps in sorbitol (polyol) pathway which is responsible for formation of fructose from glucose. Aldose reductase activity is increased, parallel to glucose blood levels, in tissues that are not insulin sensitive, including lenses, peripheral nerves and renal glomeruli. Sorbitol does not diffuse through cell membranes easily and therefore accumulates in these tissues, causing osmotic damage, leading to retinopathy and neuropathy.

雷尼司他 新