戈利昔替尼新

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货号：BCP36112CAS号：2091134-68-6纯度：98%

规格	价格(CNY)	是否现货	购买咨询
10.00 mg	￥2600.00	In-stock	购买咨询
50.00 mg	￥7000.00	In-stock	购买咨询
100.00 mg	￥11000.00	In-stock	购买咨询

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CAS号	2091134-68-6	货号	BCP36112
中文名	戈利昔替尼
英文名	Golidocitinib
中文别名
英文别名	AZD4205; AZD 4205;AZD-4205;
SMILES	CC(C(=O)NC1=CC=CC2=C1NC=C2C3=NC(=NC=C3)NC4=CN(N=C4OC)C)N5CCN(CC5)C
化学名称
分子式	C25H29N9O2	分子量	487.57
纯度	98%	配送	惯例下常温包邮
产品描述	Golidocitinib is an orally available inhibitor of Janus-associated kinase 1 (JAK1), with potential antineoplastic activity. Upon oral administration, golidocitinib inhibits JAK-dependent signaling and may lead to an inhibition of cellular proliferation in JAK1-overexpressing tumor cells. The JAK-STAT (signal transducer and activator of transcription) signaling pathway is a major mediator of cytokine activity and is often dysregulated in a variety of tumor cell types. Additionally, JAK1 may be a primary driver of STAT3 phosphorylation and signaling, which plays a role in neoplastic transformation, resistance to apoptosis, tumor angiogenesis, metastasis, immune evasion, and treatment resistance.

戈利昔替尼 新